The adiponectin concentration is a potent anti-inflammatory adipokine and acts in the regulation of insulin homeostasis, favouring the control of many chronic diseases, including atherosclerosis, hypertension, NAFLD, metabolic syndrome, cardiovascular diseases, thrombosis, and asthma [6, 7, 11, 40]. This evidence concerns the gene ADIPOQ and metabolic dysfunction-associated steatotic liver disease.