Furthermore, SALL4 expression increased significantly (p<0.001) in MDS-AML (AML patients with history of MDS) patients (74.35±20.00, n=20), but deceased (p<0.05) in post-treatment MDS patients (4.66±4.43, n=16) (Figure1B). The gene discussed is SALL4; the disease is acute myeloid leukemia.