Since MDS is a pre-leukemic stage of AML[32] and the expression pattern of SALL4 in human MDS hasn’t been intensively investigated, in this study we evaluate the expression of SALL4 in various MDS patients compared to that of Bmi-1 to explore the potential clinical prognostic value of SALL4 in MDS. This evidence concerns the gene SALL4 and acute myeloid leukemia.