In addition, we observed that SALL4 expression was higher (p<0.001) in MDS patients with high risk (50.14±14.44, n=15) karyotypes according to IPSS, including complex karyotypes (n=14) and chromosome 7 abnormalities (n=1), but lower (p<0.001) in patients with intermediate (15.53±18.62, n=8) and low risk (13.02±11.51, n=32) karyotypes (Figure 3). The gene discussed is SALL4; the disease is myelodysplastic syndrome.