CASP3 and temporal lobe epilepsy: FBJ osteosarcoma oncogene (Fos) and Caspase 3 (Casp3) were also selected due to the former’s increased expression in brain regions including hippocampus following experimentally induced seizures (e.g., via PTZ) (Popovici et al., 1990; Saffen et al., 1988) and the latter as a result of increased expression in resected neocortex from people with temporal lobe epilepsy (Henshall et al., 2000).