CD209 and infection: The discovery of HIV-1 binding to the surfaces of uninfected dendritic cells (DC) via the C-type (calcium-binding) lectin family, of which DC-SIGN is an example, has helped to elucidate complex mechanisms of transmission of internalized and stored infectious HIV-1 that appears on the surfaces of uninfected DC for trans infection of T cells [10], [13], [14], [15], [16], [17].