PLAU and cancer: The 2Chr7:1n,1d cells exhibited a more invasive phenotype by expressing higher levels of the pro-invasive genes (IGFBP2, PDGFRA, RHOC, FOXM1, and PLAU) and matrix metalloproteinase 2 (MMP2) (Figure 4A), all of which are well-reported for cancers, including GBM [36]–[38].