We investigated the DNA-PK-dependent phosphorylation of vimentin, as this major IF of mesenchymal cells plays a role in diverse cellular pathways and processes, including cell adhesion [61], [66], [67], migration [68], [69], infection [70], [71], ERK signaling [72], regulation of transcription [73] and the modulation of 14-3-3 protein-dependent signaling [74], [75]. This evidence concerns the gene PRKDC and infection.