Besides, a physical association between the HHV-6 virion and sCD46 was found in the serum of patients with MS with HHV-6 DNA, but not in the serum of controls, suggesting that the presence of HHV-6/CD46 complexes might contribute to the increased levels of CD46 found in the serum of patients with MS [45]. The gene discussed is CD46; the disease is myeloid sarcoma.