TNF and cardiovascular disorder: Regarding other putative markers of cardiovascular disease, in the control individuals, the reduced content of HDL-c was associated only with a significantly reduced concentration of adiponectin (Figure 2(a)), when compared with controls subjects with normal HDL-c levels; all the other parameters were unchanged, including hsCRP, TNF-α, uric acid, iCAM-1, and VEGF (Table 2 and Figure 2).