TLR4 and food allergy: Microflora-host interaction mediated by TLRs may play a role in the susceptibility to food allergy as hypothesized in the study by Bashir and colleagues [21] in which two groups of mice with a mutation or a deficiency of TLR-4, in contrast to TLR-4 wild type mice, showed a typical IgE-mediated immune response when exposed to allergic antigens.