Mutations in AKT1, AKT2, AKT3 genes have been identified in various forms of human cancer but only a limited number of NSCLC tumors harbor mutations in the AKT2 gene responsible for oncogenesis [36], leading to the assumption that the deregulation of the pathway is probably located at a post-transcriptional level. This evidence concerns the gene AKT1 and non-small cell lung carcinoma.