The compound will soon enter a Phase I study in combination with paclitaxel and carboplatin (with or without bevacizumab) or pemetrexed, cisplatin, and bevacizumab in patients with advanced NSCLC [80] and in combination with the EGFR inhibitor erlotinib in patients with advanced solid tumors [81]. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.