Salaria et al. [42] conclude that “The overexpression of palladin relative to normal pancreas in the majority of pancreatic cancers is limited to non-neoplastic stromal cells.” These authors conclude that, given the fact that palladin is not overexpressed in most PC cells, it then follows that palladin’s overexpression is not likely to impact the invasive and migratory abilities of PC cells. The gene discussed is PALLD; the disease is pachyonychia congenita.