However, since Mx1-Cre-mediated NEMO deletion inactivates NF-κB in all hematopoietic cells, the possibility remains that NF-κB inactivation in cells other than leukemic T cells may contribute to leukemogenesis, similarly to the role of inflammatory cells in carcinoma mouse models [73]. The gene discussed is NFKB1; the disease is carcinoma.