In other diseases SNP-131 C/G is associated with: (1) elevated plasma YKL-40 levels in patients with asthma, bronchial hyper responsiveness and pulmonary function in the Hutterites [183]; and (2) plasma YKL-40 levels and the severity of hepatitis C virus induced liver fibrosis [162]. This evidence concerns the gene CHI3L1 and Hepatic fibrosis.