CHI3L1 and non-small cell lung carcinoma: In colorectal, gastric, hepatocellular, pancreatic, non-small cell lung and ovarian adenocarcinoma YKL-40 protein expression is high compared to normal tissues [36,37,38,44] as illustrated in Figure 3C, D, H, I. In colorectal cancer (personal observation), non-small cell lung cancer [37], and ovarian cancer [36] the YKL-40 protein expression scores were not associated with prognosis.