Associations between SNPs in the VEGF-A gene and the promoter activity of the gene and protein concentrations of VEGF-A have been demonstrated in some studies [10,11] and clinical studies have also suggested association with clinical outcome in breast [12], renal cell [13], gastric [14], colorectal [15,16,17], and ovarian cancer [18]. The gene discussed is VEGFA; the disease is ovarian carcinoma.