VEGFR2 specific inhibition decreases MDSC in MDA-MB-231 xenograft and MMTV-PyMT transgenic models [50]Inhibition of both VEGFR1 and VEGFR2 increases MDSC number in the tumor in MDA-MB-231 xenograft and MMTV-PyMT transgenic models [50]. The gene discussed is FLT1; the disease is neoplasm.