Although all of these subtypes are distinct in terms of their association with precursor lesions, risk factors and mutation profiles, the high grade serous cancers feature near universal p53 mutations and genomic instability whereas low grade serous cancers, endometrioid carcinomas, mucinous carcinomas and clear cell carcinomas have relatively stable genomes and rare tp53 mutations. Here, TP53 is linked to endometrioid adenocarcinoma.