NF-κB is a transcription factor, which has an essential role in the expression of many genes whose products can suppress tumor cell death; stimulate tumor cell cycle progression; enhance epithelial-to-mesenchymal transition, which has an important role in tumor invasiveness; and provide newly emerging tumors with an inflammatory microenvironment that supports their progression, invasion of surrounding tissues, angiogenesis, and metastasis [145,146]. This evidence concerns the gene NFKB1 and neoplasm.