Of interest is that SNPs in or near genes previously identified as associated with sun-sensitive phenotypes, such as variants near the ASIP locus (which codes for the agouti protein), the tyrosinase locus (TYR) and tyrosinase related protein 1 (TYRP1) are now identified as melanoma susceptibility genes [103,104,105]. This evidence concerns the gene TYRP1 and melanoma.