TP53 and leukemia: As presented in Figure 6A and B, the effect of Bispicen on etoposide-induced apoptosis was investigated in p53-mutated leukemia cell lines, KU812 (K132R), CCRF-CEM (R175H/R248Q), and Ball-1 (D281G), and p53-null cell lines, HL60 and U937 [28-32].