Analyses of 84 key genes and other components involved in the regulation and enzymatic pathways of fatty acid and triacylglyceride metabolism revealed the upregulation of Acly, Acot3, Acsl5, Acsm3, Cpt1b, Cpt2, Fabp4, Gyk, Gpd2, HSD17B4, Lipe and Slc27a4, and downregulation of Acox2, Fabp5 and Slc27a5 (Table 3) due to FGFR4 deficiency across the breast and tumor tissues in each group. The gene discussed is HSD17B4; the disease is neoplasm.