IFN-β as a class does impact the endothelial cells and block the disintegrating effects of the IFN-γ on cerebral endothelial cells [18], decrease plasma endothelial microparticles which act as promoters of transendothelial migration of the activated leukocytes [19], protect endothelial cells from apoptosis induced by serum from MS patients [20], and decrease the expression of matrix metalloproteinases, which participate in disruption of the subendothelial matrix [21, 22]. Here, IFNB1 is linked to myeloid sarcoma.