CD40LG and Insulin resistance: Recent evidence showed that resistin, an adipokine involved in insulin resistance [91], exerts some vascular effects by inducing the expression of endothelial adhesion molecules such as VCAM-1 and ICAM-1, the endothelial production of endothelin-1, and the expression of CD40L [189]; furthermore, an association among resistin levels and markers of inflammation and fibrinolysis has been found [190]