We also found that a GBM with a MTD >4 cm, and non-clear boundary was more often to be seen in the high SAMSN1 group than in the low SAMSN1 group (p<0.1), possibly suggesting increasing proliferative and infiltrating ability of tumor cells with a higher level of SAMSN1 expression. The gene discussed is SAMSN1; the disease is glioblastoma.