(Figure 4) In cytoplasm, the scores of SAMSN1 expression in normal brain and WHO grade I – IV glioma were 1.69 ± 1.30, 5.11 ± 3.33, 5.66 ± 2.93, 5.60 ± 3.12, and 5.86 ± 3.02, respectively. The gene discussed is SAMSN1; the disease is central nervous system cancer.