The present study showed that concentrations of FABPs except for FABP2 were correlated with distinct biochemical markers reflecting tissue damage in subjects on no medication: i.e., FABP1 for liver damage, FABP3 for cardiac injury, FABP4 for adiposity and metabolic syndrome, and FABP5 for adiposity, insulin resistance, cardiac injury, and liver damage. This evidence concerns the gene FABP5 and metabolic syndrome.