Our data also demonstrated that persistent stimulation with TGFβ induced increasing cell motility and the acquisition of EMT phenotypes via the translocation of β-catenin into the cytoplasm and the nucleus in lung cancer cells, compatible with the results of previous studies, in which fibronectin and E-cadherin are involved in biomarkers of EMT [4,28-30]. This evidence concerns the gene FN1 and lung cancer.