Next, because Bcl-2 is occasionally associated with resistance to anti-tumor agents, and is often observed in human carcinomas [37], we compared the expression of Bax (pro-apoptotic) and Bcl-2 (anti-apoptotic) mRNAs, which are parts of the mitochondrial pathway, in the OSCC cells in the absence of CMA. This evidence concerns the gene BAX and neoplasm.