Consequently, we addressed the question whether rs7120118 variation affects the expression of NR1H3, ABCA1, ABCG1, and APOE. qPCR analysis showed a significant increase in the mRNA levels of NR1H3 among AD patients with the CT genotype of rs7120118 (p = 0.02) as compared to TT genotype (Figure 6A). Here, APOE is linked to Alzheimer disease.