We next investigated whether genes with strain-specific variants (Kit), involvement with steroid hormone production (Star, Cyp19a, Cyp17a1), association with PCOS (INHBB, Fem1b, Pgr, Androgen receptor, LHcgr), or involvement with gluconeogenesis or insulin signaling (Liver PepCk1, Liver IRβ, ovary IRβ, Liver G6Pase) might be involved in phenotypic differences. The gene discussed is PCK1; the disease is polycystic ovary syndrome.