At the 5% FDR level, the ANOVA model identified 12 genes in HCC whose expression varied with delay to cryopreservation (6 up-regulated: CYP2E1, IGLL1, CABYR, CLDN2, NQO1, SCL13A5 and 6 down-regulated: MT1G, MT1H, MT1E, MT1F, HABP2, SPINK1), whereas no gene expression variation in LC was observed. Here, SPINK1 is linked to hepatocellular carcinoma.