Of note, Wang et al described overexpression of CYP2E1 in HCC [55] and Maass et al. also found an increased expression of CYP2E exclusively in HCV-induced HCC and also reported over-expression of another member of the claudin family; CLDN10 in HCV-related HCC [56]. The gene discussed is CLDN10; the disease is hepatocellular carcinoma.