We initially identified these DUX4-activated transcripts in myoblasts transduced with lentivirally-expressed DUX4, but show that many of the same loci are transcribed in FSHD but not control muscle cells, indicating that endogenously expressed DUX4 can activate LTR-driven transcription in FSHD muscle. The gene discussed is DUX4; the disease is facioscapulohumeral muscular dystrophy.