Surprisingly, in addition to the four NE carcinomas, VGF was expressed at high level in eight breast carcinomas negative for CHGA and/or SYP (cases 5, 6, 7, 8, 9, 10, 11 and12) and at moderate level in cases 13, 14 and 15 (Figs. 2 and 3). This evidence concerns the gene SYP and breast carcinoma.