Because there is increasing evidence that the interplay between transcription and splicing participates in signaling pathway regulation and outcomes, we created a freely available website, named SSAS-DB (http://fasterdb.lyon.unicancer.fr/ssas-db/home.pl) that provides genome-wide information on the impact of estrogen, androgen and Ddx5/17 on gene expression in breast and prostate cancer cell lines, at both whole-gene (transcriptional) and exon- (alternative splicing) levels. This evidence concerns the gene DDX5 and Familial prostate cancer.