VEGFA and neoplasm: Macrophages also play a role in tumor growth in conjunction with lymphocytes, by synthesizing and secreting epidermal growth factor (EGF), basic fibroblast growth factor, and transforming growth factor (TGF) α and β along with other chemokines released during wound healing and inflammation, including tumor necrosis factor-α, interleukin 6, platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF) [5-9].