On univariate survival analysis tumour size (P < 0.01), tumour grade (P < 0.05), lymph node involvement (P < 0.001), Ki-67 proliferative activity (P < 0.001), lymphovascular invasion (P < 0.001) and systemic treatment (P < 0.05) were significantly associated with cancer- specific survival. This evidence concerns the gene MKI67 and cancer.