To validate this concept in other histological subtypes of NSCLC, seven additional human lung cancer cell lines (H1703, H292, H157, H1437, H460, H1650, and H358) were exposed to IL-27 for 24 hours and P-STAT1 and P-STAT3 protein levels were analyzed by Western blot. Here, IL27 is linked to non-small cell lung carcinoma.