CD177 and infection: B and T cells share features of adaptive immunity that include the ability to recognize pathogen components via clonal expression of a unique cell surface receptor; the ability to rapidly proliferate upon recognition of a pathogen, coincident with acquisition of cell lineage-specific immune functions; and finally, the ability to persist after the infection is cleared, combined with the capacity to “remember” the pathogen and respond more rapidly and vigorously upon re-infection (termed immunological memory).