NLRP3 and cryopyrin-associated periodic syndrome: Auto-activation of the NLRP3 inflammasome has been linked to several autosomal dominant cryopyrinopathies or cryopyrin-associated periodic fever syndromes (CAPS), such as familial cold-induced autoinflammatory syndrome (FCAS), Muckle–Wells syndrome (MWS), and neonatal onset multisystem inflammatory disorder or chronic infantile neurologic cutaneous and articular syndrome (NOMID/CINCA) (156).