Similarly, tumor masses produced by injection of HCT116-PLKO cells were positive for VEGF-A staining, while those produced by HCT116-Sh-hERG1 cells only showed a faint VEGF-A signal (Fig. 4S, panel B) and an even lower amount of VEGF-A transcript (see Supplementary Information). The gene discussed is KCNH2; the disease is neoplasm.