There are many hereditary pathologies, such as genetic factors, that predispose onset of colorectal carcinoma, among these the syndromes characterized by the occurrence of polyps (most of the colorectal carcinomas, approximately 80%, originated from precancerous lesions such as adenomatous polyps with dysplastic component), familial adenomatous polyps (FAP), Polyps Associated with MYH gene (MAP), Gardner's syndrome, Turcot's syndrome; and those without polyps such as Lynch's syndrome or Hereditary Non Polyposis Colorectal Carsinosis (HNPCC)[2-4]. Here, MUTYH is linked to colorectal carcinoma.