HLA-DQB1 (*02, *04, *0401, *0402 and *0601) were found to be risk factors for PBC, and the pooled ORs and 95%CI were 1.40 (1.00–1.97), 2.24 (1.46–3.46), 1.41 (1.07–1.85), 3.47 (2.35–5.13), and 1.99 (1.57–2.53), respectively (Figure S2). Here, HLA-DQB1 is linked to primary biliary cholangitis.