Conversely, HLA-DRB1 (*11, *13, *1101 and *1501) were observed to confer resistance to PBC, and the pooled results were 0.45 (0.33–0.62) and 0.31 (0.27–0.38), 0.41 (0.24–0.68), 0.82 (0.68–0.99), and 0.45 (0.31–0.65), respectively (Figure 4; Table 2). Here, HLA-DRB1 is linked to primary biliary cholangitis.