F11R and neoplasm: Based on univariate analysis, high expression of membrane JAM-A was significantly correlated with TNM stage (P = 0.021) and lymph node metastases (P = 0.007), but not with age (P = 0.818), gender (P = 0.96), differentiation (P = 0.174), tumor status (P = 0.105), and tumor histology (P = 0.818; Table 1).