Among the few overlapping genes (ULK1, INPP5K, CIB1, PRKG1, SR1, ADRBK1, GNAQ, UBE2M, PCSK1, PRKAA2) an AMPK subunit, PRKAA2, was found, further emphasizing the relevant role of AMPK in AD. This evidence concerns the gene GRK2 and Alzheimer disease.