16 cases with similar numbers of CD163+RBP-J+ and CD163+CMAF+ macrophages (M1 ≈ M2) were observed, including 7 Th1 group disease cases (4 infectious mononucleosis, 3 Crohn’s disease) and 9 Th2 group cases (1 oxyuriasis, 2 foreign body granulomas, 3 wound healing, 3 allergic nasal polyps) (Supporting Information, Table S2). Here, CD163 is linked to infectious mononucleosis.