Interestingly, results revealed that while caspase 3 activation varied slightly between the different tumor cell lines upon exposure with c9,t11-CLA, a more marked variation was observed by t10,c12-CLA treatment (Figure 4B), leading to inversely correlated measures of cell viability and caspase 3 activation (r2=0.78; P<0.01) (Figure 4C). This evidence concerns the gene CASP3 and neoplasm.