Distribution of CXCL1 genotypes (GG, GA, AA) was 159 (34.7%), 219 (47.8%), 80 (17.5%) in cirrhotic patients with or without HCC, 52 (45.2%), 44 (38.3%), 19 (16.5%) in alcoholic controls and 158 (46.2%), 140 (40.9%), 44 (12.9%) in healthy controls. The gene discussed is CXCL1; the disease is hepatocellular carcinoma.