Their quiescent nature is evidenced by upregulation of a series of genes with a role in anti-growth, tumor suppression, anti-development, and anti-differentiation (TXNIP, LOX, NBPF, ATP13A3, RASSF8, PDLIM5, PRRG4, BAT2D1, MOBKL1B, PPP2R1A, RPL38, SF3B1). Here, PDLIM5 is linked to neoplasm.