MMP9 and neoplasm: Consistently, TGF-β1/H2O2/HOCl was most efficient in promoting the polymerization of actin in tumor cells (Figure 1C) and the production of active MMP-2 and MMP-9 by tumor cells (Figure 1D) in response to ECM molecules (matrigel), which are important for migratory and invasive properties of tumor cells [18]–[20].