We applied the threshold for scoring methylation-positive samples from the test series and found the following individual promoter-methylation frequencies of DSP, FZD8, KCNH2, and PPP1R14A across the different NHL types in the validation series: 40% (10/25), 60% (15/25), 40% (10/25), and 60% (15/25), respectively (Figure 3 and Table 3). Here, FZD8 is linked to non-Hodgkin lymphoma.