CP and tuberculosis: The SMFA analysis of sera collected after a single dose of Pfs25-CP VLPs showed 100% TB activity on study day 70 in mice that received ≥5.0 μg of the Pfs25 equivalent in the VLPs, whereas doses of 1.0 and 0.2 μg of the Pfs25 equivalent elicited >99.5% and 98.8% reduction, respectively (Table 3).