In this study, we accounted for the following factors: the PCOS ovarian tissue morphology and structural changes, ovarian expression of P450arom, P450c17α and their mRNA, and steroid hormones (i.e., testosterone, androstenedione, estradiol, and estrone) levels related to the synthesis or catalysis of the 2 enzymes. This evidence concerns the gene CYP19A1 and polycystic ovary syndrome.